In Hot Pursuit of the Elusive Heat Transducers

ceptors, and following the cloning of VR1 the search for If the fire is near the foot, the particles of this fire... have other vanilloid receptor family members began. To date, the power to move the area of the skin of this foot that three related molecules have been identified. The vanilthey touch... at the same instant they open the entrance loid receptor–like protein subtype 1 (VRL-1) does not of the pore or little conduit. respond to capsaicin or acid but is activated by temper—Rene Descartes, Traite de Homme (1662). atures higher than about 528C (Caterina et al., 1999).